The Office's staff number peaked in 1991, at 54. In that year, 28 staff members held regular posts (11 professional, 17 general-service posts). The other 26 occupied project posts (12 professional, 14 general-service).

Currently, the Office has a total of 29 staff members. Of these 27 are in regular posts (14 professional, 15 general service). The remaining 2are in project posts . There are also 15 staff on Special Service Agreement. staff is as listed below. For each category, staff members are arranged alphabetically by last names, written in CAPITALS. Official titles are shown in (parentheses).

Mr. Joseph M.G. Massaquoi
Director, UNESCO Nairobi Office and Regional Bureau for Science and Technology in Africa

Ms. Susanne Buttkus
Administrative Officer

• Abou AMANI (Regional Hydrologist)
• Dorothy ACHIENG (Librarian/Focal Point for Portal Development)
• Bernadette ASSISI-Ogolla (Registry Clerk)
• Maurice ASUDI (Financial and Accounting Assistant)
• Moritz BILAGHER (Statistical Cluster Advisor)
• Peggy BOATENG (Consultant/Programme Specialist, Basic & Engineering Sciences)
• Christophe Kwami DIKENOU (Consultant, Social & Human Sciences)
• Hezekiel DLAMINI (Regional Communication Advisor)
• Vick IKOBWA (National Professional Officer)
• Jane KAMAU (National Programme Officer- HIV/AIDS, Kenya)
• Elizabeth KARANJA (Director's Secretary)
• Isaac KING'OO (Machine Operator)
• Lydiah KINITI (Programme CI)
• Charles MATEDECHA (Driver)
• Stefano MAZZILLI ( Associate Expert /JPO)
• Mary MATEMU (Administrative Assistant)
• Julie MERAB (Administrative Assistant- HRM)
• Margaret MUIGAI (Director's Secretary- retiring)
• George MUSUNGU (Messenger)
• Elizabeth Mwakelemu (Public Information Assistant)
• John MWAKITELE (Administrative Clerk/Procurement)
• Joseph NJOROGE (Project: Junior Clerk)
• Alice OCHANDA (National Programme Officer - Liaison )
• Mika ODIDO (Head Intergovernmental Oceanographic Commission (IOC)WIO/OdinAfrica)
• Fumiko OHINATA (Programme Specialist for Culture)
• Georgette OMOLO (Secretary)
• Noeline RAKOTOARISOA (Programme Specialist for Ecology)
• Subramaniyam VENKANTRAMAN (Technical Specialist. Literacy, Monitoring and Evaluation in Education)
• Segi-VTLCHEK (Education Programme Specialist)

Education Field Personnel

• Aimable UWURUKUNDO (National Programme Office- HIV & AIDS -Rwanda)
• Bernadin RUTAZIBWA (Antennae Office, National Professional Office-  Rwanda)
• Charles DRAECABO (Uganda National Officer- HIV & AIDS- Uganda)
• Ronald BIRYAHWAHO (Uganda EDUCAIDS Technical Specialist - Rwanda

Staff on Special Service Agreement

• Rita ANYUMBA (Programme Assistant, Hydrology)
• Anne KIOKO (Programme Assistant, Education)
• David KIRENGA (Regional Science Programme Assistant)
• Jacqueline MENGO (Secretary)
• Kenneth, MUCHIRI (Administrative Assistant)
• Eunice NJUGUNA (Logistics Assistant)
• Pamela OTIENO (Programme Assistant, Culture)